Download full text in PDF
Vorobets PY. Dynamics of the content of trace elements in royal jelly of different breeds (subspecies) of honey bees depending on the month of its collection. Bìol Tvarin. 2025; 27 (4): 64–69. DOI: 10.15407/animbiol27.04.073.
https://doi.org/10.15407/animbiol27.04.073
Received 05.08.2025 ▪ Revision 11.10.2025 ▪ Accepted 01.11.2025 ▪ Published online 16.02.2026
Dynamics of the content of trace elements in royal jelly of different breeds (subspecies) of honey bees depending on the month of its collection
P. Y. Vorobets
This email address is being protected from spambots. You need JavaScript enabled to view it.
Institute of Animal Biology NAAS, 38 V. Stusa str., Lviv, 79034, Ukraine
Royal jelly is a unique product of worker bees, namely the secret of their pharyngeal and maxillary glands. It is the main source of nutrients and biologically active substances for larvae and queens. Royal jelly includes a wide range of macro- and microelements that play a key role in the development of the bee colony, regulation of metabolism. Royal jelly is promising for use in medicine, pharmacy, cosmetology, etc. Comparative study of the mineral composition of royal jelly obtained from different breeds of bees and at different times of the year is important for understanding the biochemical mechanisms of its secretion and optimizing the technological conditions for obtaining this product with the highest possible biological value. The aim of the work was to compare changes in the content of copper (Cu), manganese (Mn), zinc (Zn), cobalt (Co) and nickel (Ni) in royal jelly obtained at different times, namely: in May, June and July from honey bees of four breeds (subspecies) — Carpathian bee (Apis mellifera carpatica), Carniolan bee (Apis mellifera carnica), Italian bee (Apis mellifera ligustica) and Ukrainian steppe bee (Apis mellifera sossimai). As a result of the study, the variability of changes in the content of trace elements in royal jelly of the studied breeds (subspecies) of bees depending on the period of its obtaining was established.
Key words: royal jelly, trace elements, Apis mellifera carpatica, Apis mellifera carnica, Apis mellifera ligustica, Apis mellifera sossimai
- Balkanska R, Mladenova E, Karadjova I. Quantification of selected trace and mineral elements in royal jelly from bulgaria by ICP-OES and ETAAS. J Apic Sci. 2017; 61 (2): 223–232. DOI: 10.1515/jas-2017-0021.
- Botezan S, Baci GM, Bagameri L, Pașca C, Dezmirean DS. Current status of the bioactive properties of royal jelly: A comprehensive review with a focus on its anticancer, anti-inflammatory, and antioxidant effects. Molecules. 2023; 28 (3): 1510. DOI: 10.3390/molecules28031510.
- Collazo N, Carpena M, Nuñez-Estevez B, Otero P, Simal-Gandara J, Prieto MA. Health promoting properties of bee royal jelly: Food of the Nutrients. 2021; 13 (2): 543. DOI: 10.3390/nu13020543.
- Fratini F, Cilia G, Mancini S, Felicioli A. Royal jelly: An ancient remedy with remarkable antibacterial properties. Microbiol Res. 2016; 192: 130–141. DOI: 10.1016/j.micres.2016.06.007.
- Garcia-Amoedo LH, De Almeida-Muradian LB. Physicochemical composition of pure and adulterated royal jelly. Quim Nova. 2007; 30 (2): 257–259. DOI: 10.1590/S0100-40422007000200002.
- Ghosh S, Jang H, Sun S, Jung C. Nutrient composition and quality assessment of royal jelly samples relative to feed supplements. Foods. 2024; 13 (12): 1942. DOI: 10.3390/foods13121942.
- Kunugi H, Ali AM. Royal jelly and its components promote healthy aging and longevity: From animal models to humans. Int J Mol Sci. 2019; 20 (19): 4662. DOI: 10.3390/ijms20194662.
- Maleki V, Jafari-Vayghan H, Saleh-Ghadimi S, Adibian M, Kheirouri S, Alizadeh M. Effects of royal jelly on metabolic variables in diabetes mellitus: A systematic review. Complem Ther Med. 2019; 43: 20–27. DOI: 10.1016/j.ctim.2018.12.022.
- Petrovska IR, Salyha YT, Vudmaska IV. Statistical Methods in Biological Research. The educational and methodological manual. Kyiv, Agrarian Science; 2022: 172 p. ISBN 978-966-540-551-1. (in Ukrainian)
- Sabatini AG, Marcazzan GL, Caboni MF, Bogdanov S, de Almeida-Muradian LB. Quality and standardisation of royal Jelly. J ApiProd ApiMed Sci. 2009; 1 (1): 1–6. DOI: 10.3896/IBRA.4.01.1.04.
- Stocker A, Schramel P, Kettrup A, Bengsch E. Trace and mineral elements in royal jelly and homeostatic effects. J Trace Elem Med Biol. 2005; 19 (2–3): 183–189. DOI: 10.1016/j.jtemb.2005.08.004.
- Wang Y, Ma L, Zhang W, Cui X, Wang H, Xu B. Comparison of the nutrient composition of royal jelly and worker jelly of honey bees (Apis mellifera). Apidologie. 2016; 47: 48–56. DOI: 10.1007/s13592-015-0374-x.
- Yu X, Tu X, Tao L, Daddam J, Li S, Hu F. Royal jelly fatty acids: Chemical composition, extraction, biological activity, and prospect. J Funct Foods. 2023; 111: 105868. DOI: 10.1016/j.jff.2023.105868.














