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Kuryata NV, Chechet OM, Gorbatyuk OI, Pishchanskyi OV, Balanchuk LV, Mekh NY, Zhovnir OM. Fluoroquinolone-resistant Escherichia coli strains in animal and poultry feed from Ukrainian feed-producing enterprises. Bìol Tvarin. 2025; 27 (1): 9–14. DOI: 10.15407/animbiol27.01.009.
https://doi.org/10.15407/animbiol27.01.009
Received 07.06.2024 ▪ Revision 05.02.2025 ▪ Accepted 20.03.2025 ▪ Published online 11.04.2025

Fluoroquinolone-resistant Escherichia coli strains in animal and poultry feed from Ukrainian feed-producing enterprises

N. V. Kuryata¹, O. M. Chechet², O. I. Gorbatyuk², O. V. Pishchanskyi², L. V. Balanchuk², N. Y. Mekh², O. M. Zhovnir³
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¹Institute of Animal Biology NAAS, 38 V. Stus str. Lviv, 79034, Ukraine
²State Research Institute for Laboratory Diagnostics and Veterinary and Sanitary Expertise, 30 Donetska str. Kyiv, 03151, Ukraine
³Institute of Veterinary Medicine NAAS, 30 Donetska str., Kyiv, 03151, Ukraine

The article presents the results of studying the sensitivity of Escherichia coli strains isolated from animal and poultry feed samples to fluoroquinolones of the second (ofloxacin, norfloxacin), third (levofloxacin) and fourth (moxifloxacin) generations. It was shown that high resistance to norfloxacin was detected in 7 strains of isolated E. coli, which accounted for 33.3% of the identified ones. To ofloxacin and to the representative of the third generation of fluoroquinolones — levofloxacin, 3 isolated strains of E. coli were resistant, which was 14.3% of the studied strains. Resistance to the representative of the fourth generation of fluoroquinolones — moxifloxacin — was detected in 1 strain of E. coli, which was 4.8% of the tested strains. The results of the studies on fluoroquinolone resistance of the isolated E. coli strains indicate a significant contamination of animal and poultry feed with fluoroquinolone-resistant escherichia. This poses potential risks for the spread and possible transmission of such resistance to other bacterial species and the normobiota of the gastrointestinal tract of animals, poultry when ingested with feed and humans when consuming products of animal origin after feeding such feed.

Key words: Escherichia coli, fluoroquinolones, mixed fodder, bran, meal, premixes, animal meal, fish meal

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